Adverse Drug Events during AKI and Its Recovery

Adverse drug events during AKI and its recovery.

BACKGROUND AND OBJECTIVES The impact of AKI on adverse drug events and therapeutic failures and the medication errors leading to these events have not been well described. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS A single-center observational study of 396 hospitalized patients with a minimum 0.5 mg/dl change in serum creatinine who were prescribed a nephrotoxic or renally eliminated medi...

Anticoagulation-associated adverse drug events.

PURPOSE Anticoagulant drugs are among the most common medications that cause adverse drug events (ADEs) in hospitalized patients. We performed a 5-year retrospective study at Brigham and Women's Hospital to determine clinical characteristics, types, root causes, and outcomes of anticoagulant-associated ADEs. METHODS We reviewed all inpatient anticoagulant-associated ADEs, including adverse dr...

HIV-related TB and adverse drug events.

Choosing appropriate theories for understanding hospital reporting of adverse drug events, a theoretical domains framework approach

Adverse drug events (ADEs) may cause serious injuries including death. Spontaneous reporting of ADEs plays a great role in detection and prevention of them, however, underreporting always exists. Although several interventions have been utilized to solve this problem, they are mainly based on experience and the rationale for choosing them has no theoretical base. The vast variety of behavioral ...

Systems analysis of adverse drug events.

Objective.\p=m-\To identify and evaluate the systems failures that underlie errors causing adverse drug events (ADEs) and potential ADEs. Design.\p=m-\Systemsanalysis of events from a prospective cohort study. Participants.\p=m-\Alladmissions to 11 medical and surgical units in two tertiary care hospitals over a 6-month period. Main Outcome Measures.\p=m-\Errors,proximal causes, and systems fai...